KA MOOLELO O GELATIN CAPSULES
ʻO ka mea mua, ʻike mākou a pau he paʻakikī ke ale ʻana i nā lāʻau lapaʻau, hele pinepine ʻia me kahi ʻala maikaʻi ʻole a i ʻole ka ʻono ʻawaʻawa. o ka lapaau ana.ʻO kekahi pilikia ʻē aʻe a nā kauka a me nā mea maʻi i alo i ka wā ma mua, ʻaʻole hiki ke ana pololei i ke ʻano a me ka neʻe ʻana o kahi lāʻau lapaʻau no ka mea ʻaʻohe kūlike quantitative standard.
I ka makahiki 1833, ua hoʻomohala kekahi kanaka lapaʻau Farani ʻōpio, ʻo Mothes, i nā capsule palupalu gelatin.Hoʻohana ʻo ia i kahi ʻano e hoʻopili ʻia ai kahi ʻano kikoʻī o kahi lāʻau lapaʻau i loko o kahi solution gelatin wela e paʻa i ka wā e maʻalili e pale i ka lāʻau.ʻOiai e ʻai ana i ka capsule, ʻaʻole loaʻa i ka mea maʻi ka manawa e ʻono ai i ka mea hoʻoikaika o ka lāʻau.
Ua kaulana ʻo Gelatin capsules a ua ʻike ʻia ʻo ia ka excipient maikaʻi loa no ka lāʻau lapaʻau, ʻoiai ʻo ka gelatin wale nō ka mea i hoʻoheheʻe ʻia i ka mahana o ke kino.I ka makahiki 1874, ua hoʻokumu ʻo James Murdock ma Lākana i ka pahu gelatin paʻakikī mua loa o ka honua me kahi pāpale a me kahi kino capsule.
Ma ka hopena o ke kenekulia 19, ua alakaʻi nā ʻAmelika i ka hoʻomohala ʻana i nā capsules gelatin.Ma waena o 1894 a me 1897, ua kūkulu ʻia e ka hui lāʻau lapaʻau ʻAmelika ʻo Eli Lilly i kāna hale hana kaila gelatin mua no ka hana ʻana i kahi ʻano hou o nā ʻāpana ʻelua, ʻo ka capsule hoʻopaʻa paʻa ponoʻī.
I ka makahiki 1930, ua hana hou ʻo Robert P. Scherer ma o ka hoʻomohala ʻana i kahi mīkini hoʻopihapiha hoʻopihapiha hoʻomau, i hiki ke hana nui ʻia nā capsules.
ʻOi aku ma mua o 100 mau makahiki, ʻo ka gelatin ka mea nui i koho ʻia no nā capsules paʻakikī a palupalu a hoʻohana nui ʻia.
Ka manawa hoʻouna: Iune-23-2021
